METALLOTHIONEINS PROTECT AGAINST OBESE-INDUCED OXIDATIVE STRESS IN YOUNG WOMEN

Abstract

Obesity is rapidly increasing all over the world and pretends to be the global medical and social problem. Frequency of persons with overweight and obesity in the world has doubled since 1980, and by 2016, more than 1.9 billion adults with overweight and over 650 million with obesity, the main part of which belongs to young people (http://www.who.int/mediacentre/factsheets/fs311/en/). Because the oxidative stress is the main cause of progress of different pathologies and not too much is known about this phenomena under obesity, we were inspired to study the parameters of oxidative stress, concentration of multifunctional stress-related and metal-binding proteins metallothioneins and the level of molecular lesions in the blood of obese women (32 < body mass index < 37).