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|Title:||WATERBORNE SUCROSE IMPAIRS HEALTH STATUS OF FARMING FISH CARASSIUS AURATVS GIBELIO|
|Bibliographic description (Ukraine):||Waterborne sucrose impairs health status of farming fish Carassius auratus gibelio / H. Falfushynska et al. // 19'h International multidisciplinary scientific geoconference : SGEM 2019. Sofia, 2019. Vol. 19, issue 6.1. P. 1045–1052|
|Abstract:||Glucose toxicity is a well-established being that has been proven in higher vertebrates. The goal of this the present study was to elucidate the response of farming fish gibel carp Carassius auralus gibelio to waterborne sucrose in low (5.55 mM, LS) and high (55.5 mM, HS) concentrations for 21 days mimicking carbohydrate-enrich diet. An increase in blood glucose levels, body mass and hepatosomatic indices were the common sign for both concentrations of sucrose. The treatment with low concentration of sucrose provoked prominent manifestations of oxidative stress traits, namely enhancement of reactive oxygen species (ROS), lipid peroxidation and lipofuscin in the liver. In contrast, exposure of fish to HS induced the oppression of stress response: the decreasing the levels of ROS and lipid peroxidation, accompanied by the elevation of DNA strand break, depletion of cholinesterase activity and enhancing of glycated hemoglobin. Treatment of carp with HS caused 50% mortality for 21 days. Substantially that hyperglycemia in LS and HS groups were accompanied by significant upregulation of stress-related proteins metallothioneins in the liver. Overall, gibel carp represents the prospective model for study hyperglycemia mechanisms and consequences in vertebrates. The appropriate level of carbohydrate in the diet of the farming fish is essential.|
|Appears in Collections:||Тези конференцій (міжфакультетні)|
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